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The Kinetics of Amyloid Fibrillar Aggregation of Uperin 3.5 Is Directed by the Peptide's Secondary Structure
Many peptides aggregate into insoluble β-sheet rich amyloid fibrils. Some of these aggregation processes are linked to age-related …
Torsten John
,
Tiara J. A. Dealey
,
Nicholas P. Gray
,
Nitin A. Patil
,
Mohammed A. Hossain
,
Bernd Abel
,
John A. Carver
,
Yuning Hong
,
Lisandra L. Martin
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Impact of nanoparticles on amyloid peptide and protein aggregation: a review with a focus on gold nanoparticles
Society is increasingly exposed to nanoparticles as they are ubiquitous in nature and introduced as man-made air pollutants and as …
Torsten John
,
Anika Gladytz
,
Clemens Kubeil
,
Lisandra L. Martin
,
Herre Jelger Risselada
,
Bernd Abel
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The Quartz Crystal Microbalance with Dissipation Monitoring (QCM-D) Technique Applied to the Study of Membrane-Active Peptides
Membrane-active peptides, such as antimicrobial, amyloidogenic or cell-penetrating peptides fulfil complex functions in organisms and …
Torsten John
,
Bernd Abel
,
Lisandra L. Martin
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DOI
Amyloid aggregation and membrane activity of the antimicrobial peptide uperin 3.5
Amyloid fibrils are highly ordered, β-sheet rich forms of aggregated peptides and proteins that are associated with a variety of …
Lisandra L. Martin
,
Clemens Kubeil
,
Stefania Piantavigna
,
Tarun Tikkoo
,
Nicholas P. Gray
,
Torsten John
,
Antonio N. Calabrese
,
Yanqin Liu
,
Yuning Hong
,
Mohammed A. Hossain
,
Nitin Patil
,
Bernd Abel
,
Ralf Hoffmann
,
John H. Bowie
,
John A. Carver
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How kanamycin A interacts with bacterial and mammalian mimetic membranes
Biological membranes are natural barriers to the transport of molecules and drugs within human bodies. Many antibacterial agents need …
Torsten John
,
Trayder Thomas
,
Bernd Abel
,
Bayden R. Wood
,
David K. Chalmers
,
Lisandra L. Martin
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DOI
Effects of guanidino modified aminoglycosides on mammalian membranes studied using a quartz crystal microbalance
The increase in bacterial and viral resistance to current therapeutics has led to intensive research for new antibacterial and …
Torsten John
,
Zhi Xiang Voo
,
Clemens Kubeil
,
Bernd Abel
,
Bim Graham
,
Leone Spiccia
,
Lisandra L. Martin
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Peptides@mica: from affinity to adhesion mechanism
Investigating the adsorption of peptides on inorganic surfaces, on the molecular level, is fundamental for medicinal and analytical …
Anika Gladytz
,
Torsten John
,
Thomas Gladytz
,
Rayk Hassert
,
Mareen Pagel
,
Herre Jelger Risselada
,
Sergej Naumov
,
Annette G. Beck-Sickinger
,
Bernd Abel
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Multifunctional Coating Improves Cell Adhesion on Titanium by using Cooperatively Acting Peptides
Promotion of cell adhesion on biomaterials is crucial for the long-term success of a titanium implant. Herein a novel concept is …
Mareen Pagel
,
Rayk Hassert
,
Torsten John
,
Klaus Braun
,
Manfred Wießler
,
Bernd Abel
,
Annette G. Beck-Sickinger
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