Engineering Bionanomaterials

Our research aims to manipulate the structural properties of bionanomaterials for applications in targeted drug delivery, biosensing, and cell interaction modulation. We employ DNA origami technology to engineer functional nanoscale materials, achieving precise assembly through DNA strand modifications.

Related Publications

^{Jeffrey Gorman, Stephanie M. Hart, Torsten John, Maria A. Castellanos, Dvir Harris, Molly F. Parsons, James L. Banal, Adam P. Willard, Gabriela S. Schlau-Cohen, Mark Bathe (2024). Sculpting photoproducts with DNA origami. Chem. https://doi.org/10.1016/j.chempr.2024.03.007}

^{Stephen O. Aderinto, Torsten John, Abdulmujeeb Onawole, Raphael Peter Galleh, Jim A. Thomas (2024). Iridium(III)-based minor groove binding complexes as DNA photocleavage agents. Dalton Transactions. https://doi.org/10.1039/d4dt00171k}

^{Xiao Wang, Shanshan Li, Hyungmin Jun, Torsten John, Kaiming Zhang, Hannah Fowler, Jonathan PK Doye, Wah Chiu, Mark Bathe (2022). Planar 2D wireframe DNA origami. Science Advances. https://doi.org/10.1126/sciadv.abn0039}

^{Hyungmin Jun, Xiao Wang, Molly F Parsons, William P Bricker, Torsten John, Shanshan Li, Steve Jackson, Wah Chiu, Mark Bathe (2021). Rapid prototyping of arbitrary 2D and 3D wireframe DNA origami. Nucleic Acids Research. https://doi.org/10.1093/nar/gkab762}