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Functionalizing Nucleic Acids: Synthesis and Purification Strategies for Bioconjugates as Biomaterials
Nucleic acids are fundamental to life, encoding and storing genetic information, catalyzing biological processes, and directing protein …
Nico Alleva
,
Jian Zhang
,
David Y. W. Ng
,
Tanja Weil
,
Torsten John
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Co‐Assemblies Regulate the Catalytic Activity of Peptide Fibrils
Short peptide sequences self-assemble into supramolecular structures through intermolecular interactions, creating a microenvironment …
Albin Lahu
,
Shao‐Lin Wu
,
Maximilian Schuler
,
Francesca Mazzotta
,
Ardit Ramadani
,
Emirhan Koca
,
Ingo Lieberwirth
,
Katharina Landfester
,
Torsten John
,
David Y. W. Ng
,
Tanja Weil
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Design of the Hydrophobic Core of Self-Assembling Peptide Fibrils for Enhanced Neural Regeneration
Neurons have limited self-repair ability, and typical treatment approaches for damaged tissue rely on surgery. Hindered by the lack of …
Yu-Liang Tsai
,
Primiana Cavallo
,
Qi Lu
,
Jiyao Yu
,
Christopher P. Ender
,
Julian Link
,
Katrin Amann-Winkel
,
Kristina Endres
,
Christopher v. Synatschke
,
Torsten John
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Self‐Assembly of Amphiphilic Polyphenylene Dendrimers with Different Surface Functionalization in Solvent/Non‐Solvent Mixtures
This work compares the self-assembly of nanometer-sized amphiphilic Janus-type and patched polyphenylene dendrimers (PPDs) in …
Svenja Weigold
,
Kerstin Brödner
,
Torsten John
,
Jan Freudenberg
,
Uwe H. F. Bunz
,
Tanja Weil
,
George Fytas
,
Klaus Müllen
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Hybrid Materials From Peptide Nanofibrils and Magnetic Beads to Concentrate and Isolate Virus Particles
Peptide nanofibrils (PNFs) are considered a novel and highly efficient class of retroviral transduction enhancers due to their ability …
Manuel Hayn
,
Torsten John
,
Juhaina Bandak
,
Lena Rauch‐Wirth
,
Bernd Abel
,
Jan Münch
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Sculpting photoproducts with DNA origami
Natural light-harvesting systems spatially organize densely packed dyes in different configurations to either transport excitons or …
Jeffrey Gorman
,
Stephanie M. Hart
,
Torsten John
,
Maria A. Castellanos
,
Dvir Harris
,
Molly F. Parsons
,
James L. Banal
,
Adam P. Willard
,
Gabriela S. Schlau-Cohen
,
Mark Bathe
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Iridium(III)-based minor groove binding complexes as DNA photocleavage agents
Transition metal complexes containing the qtpy ligand (2′:4,4′′:4′,4′′′-quaterpyridyl) are known to be DNA intercalators or minor …
Stephen O. Aderinto
,
Torsten John
,
Abdulmujeeb Onawole
,
Raphael Peter Galleh
,
Jim A. Thomas
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Molecular Insights into the Dynamics of Amyloid Fibril Growth: Elongation and Lateral Assembly of GNNQQNY Protofibrils
The self-assembly of peptides and proteins into β-sheet rich amyloid fibrils is linked to both functional and pathological states. In …
Torsten John
,
Aldo Rampioni
,
David Poger
,
Alan E. Mark
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Peptide Self‐Assembly into Amyloid Fibrils at Hard and Soft Interfaces – From Corona Formation to Membrane Activity
Peptides and proteins are exposed to a variety of interfaces in a physiological environment, such as cell membranes, protein …
Torsten John
,
Lisandra L. Martin
,
Bernd Abel
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Lipid oxidation controls peptide self-assembly near membranes through a surface attraction mechanism
The self-assembly of peptides into supramolecular structures has been linked to neurodegenerative diseases but has also been observed …
Torsten John
,
Stefania Piantavigna
,
Tiara J. A. Dealey
,
Bernd Abel
,
Herre Jelger Risselada
,
Lisandra L. Martin
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