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Curvature model for nanoparticle size effects on peptide fibril stability and molecular dynamics simulation data
Nanostructured surfaces are widespread in nature and are being further developed in materials science. This makes them highly relevant …
Torsten John
,
Lisandra L. Martin
,
Herre Jelger Risselada
,
Bernd Abel
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Mechanistic insights into the size-dependent effects of nanoparticles on inhibiting and accelerating amyloid fibril formation
The aggregation of peptides into amyloid fibrils has been linked to ageing-related diseases, such as Alzheimer’s and type 2 …
Torsten John
,
Juliane Adler
,
Christian Elsner
,
Johannes Petzold
,
Martin Krueger
,
Lisandra L. Martin
,
Daniel Huster
,
Herre Jelger Risselada
,
Bernd Abel
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Planar 2D wireframe DNA origami
Two-dimensional (2D) DNA origami is widely used for applications ranging from excitonics to single-molecule biophysics. Conventional, …
Xiao Wang
,
Shanshan Li
,
Hyungmin Jun
,
Torsten John
,
Kaiming Zhang
,
Hannah Fowler
,
Jonathan P. K. Doye
,
Wah Chiu
,
Mark Bathe
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Rapid prototyping of arbitrary 2D and 3D wireframe DNA origami
Wireframe DNA origami assemblies can now be programmed automatically from the top-down using simple wireframe target geometries, or …
Hyungmin Jun
,
Xiao Wang
,
Molly F. Parsons
,
William P. Bricker
,
Torsten John
,
Shanshan Li
,
Steve Jackson
,
Wah Chiu
,
Mark Bathe
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Growth, Polymorphism, and Spatially Controlled Surface Immobilization of Biotinylated Variants of IAPP 21–27 Fibrils
The islet amyloid polypeptide (IAPP) is a regulatory peptide that can aggregate into fibrillar structures associated with type 2 …
Torsten John
,
Juhaina Bandak
,
Nilushiya Sarveson
,
Claudia Hackl
,
Herre Jelger Risselada
,
Andrea Prager
,
Christian Elsner
,
Bernd Abel
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Adsorption of Amyloidogenic Peptides to Functionalized Surfaces Is Biased by Charge and Hydrophilicity
Surfaces are abundant in living systems, such as in the form of cellular membranes, and govern many biological processes. In this …
Torsten John
,
George W. Greene
,
Nitin A. Patil
,
Tiara J. A. Dealey
,
Mohammed A. Hossain
,
Bernd Abel
,
Lisandra L. Martin
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The Kinetics of Amyloid Fibrillar Aggregation of Uperin 3.5 Is Directed by the Peptide's Secondary Structure
Many peptides aggregate into insoluble β-sheet rich amyloid fibrils. Some of these aggregation processes are linked to age-related …
Torsten John
,
Tiara J. A. Dealey
,
Nicholas P. Gray
,
Nitin A. Patil
,
Mohammed A. Hossain
,
Bernd Abel
,
John A. Carver
,
Yuning Hong
,
Lisandra L. Martin
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Impact of nanoparticles on amyloid peptide and protein aggregation: a review with a focus on gold nanoparticles
Society is increasingly exposed to nanoparticles as they are ubiquitous in nature and introduced as man-made air pollutants and as …
Torsten John
,
Anika Gladytz
,
Clemens Kubeil
,
Lisandra L. Martin
,
Herre Jelger Risselada
,
Bernd Abel
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The Quartz Crystal Microbalance with Dissipation Monitoring (QCM-D) Technique Applied to the Study of Membrane-Active Peptides
Membrane-active peptides, such as antimicrobial, amyloidogenic or cell-penetrating peptides fulfil complex functions in organisms and …
Torsten John
,
Bernd Abel
,
Lisandra L. Martin
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Amyloid aggregation and membrane activity of the antimicrobial peptide uperin 3.5
Amyloid fibrils are highly ordered, β-sheet rich forms of aggregated peptides and proteins that are associated with a variety of …
Lisandra L. Martin
,
Clemens Kubeil
,
Stefania Piantavigna
,
Tarun Tikkoo
,
Nicholas P. Gray
,
Torsten John
,
Antonio N. Calabrese
,
Yanqin Liu
,
Yuning Hong
,
Mohammed A. Hossain
,
Nitin Patil
,
Bernd Abel
,
Ralf Hoffmann
,
John H. Bowie
,
John A. Carver
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