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Planar 2D wireframe DNA origami
Two-dimensional (2D) DNA origami is widely used for applications ranging from excitonics to single-molecule biophysics. Conventional, …
Xiao Wang
,
Shanshan Li
,
Hyungmin Jun
,
Torsten John
,
Kaiming Zhang
,
Hannah Fowler
,
Jonathan P. K. Doye
,
Wah Chiu
,
Mark Bathe
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Rapid prototyping of arbitrary 2D and 3D wireframe DNA origami
Wireframe DNA origami assemblies can now be programmed automatically from the top-down using simple wireframe target geometries, or …
Hyungmin Jun
,
Xiao Wang
,
Molly F. Parsons
,
William P. Bricker
,
Torsten John
,
Shanshan Li
,
Steve Jackson
,
Wah Chiu
,
Mark Bathe
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Growth, Polymorphism, and Spatially Controlled Surface Immobilization of Biotinylated Variants of IAPP 21–27 Fibrils
The islet amyloid polypeptide (IAPP) is a regulatory peptide that can aggregate into fibrillar structures associated with type 2 …
Torsten John
,
Juhaina Bandak
,
Nilushiya Sarveson
,
Claudia Hackl
,
Herre Jelger Risselada
,
Andrea Prager
,
Christian Elsner
,
Bernd Abel
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Adsorption of Amyloidogenic Peptides to Functionalized Surfaces Is Biased by Charge and Hydrophilicity
Surfaces are abundant in living systems, such as in the form of cellular membranes, and govern many biological processes. In this …
Torsten John
,
George W. Greene
,
Nitin A. Patil
,
Tiara J. A. Dealey
,
Mohammed A. Hossain
,
Bernd Abel
,
Lisandra L. Martin
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The Kinetics of Amyloid Fibrillar Aggregation of Uperin 3.5 Is Directed by the Peptide's Secondary Structure
Many peptides aggregate into insoluble β-sheet rich amyloid fibrils. Some of these aggregation processes are linked to age-related …
Torsten John
,
Tiara J. A. Dealey
,
Nicholas P. Gray
,
Nitin A. Patil
,
Mohammed A. Hossain
,
Bernd Abel
,
John A. Carver
,
Yuning Hong
,
Lisandra L. Martin
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Amyloid aggregation and membrane activity of the antimicrobial peptide uperin 3.5
Amyloid fibrils are highly ordered, β-sheet rich forms of aggregated peptides and proteins that are associated with a variety of …
Lisandra L. Martin
,
Clemens Kubeil
,
Stefania Piantavigna
,
Tarun Tikkoo
,
Nicholas P. Gray
,
Torsten John
,
Antonio N. Calabrese
,
Yanqin Liu
,
Yuning Hong
,
Mohammed A. Hossain
,
Nitin Patil
,
Bernd Abel
,
Ralf Hoffmann
,
John H. Bowie
,
John A. Carver
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How kanamycin A interacts with bacterial and mammalian mimetic membranes
Biological membranes are natural barriers to the transport of molecules and drugs within human bodies. Many antibacterial agents need …
Torsten John
,
Trayder Thomas
,
Bernd Abel
,
Bayden R. Wood
,
David K. Chalmers
,
Lisandra L. Martin
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Effects of guanidino modified aminoglycosides on mammalian membranes studied using a quartz crystal microbalance
The increase in bacterial and viral resistance to current therapeutics has led to intensive research for new antibacterial and …
Torsten John
,
Zhi Xiang Voo
,
Clemens Kubeil
,
Bernd Abel
,
Bim Graham
,
Leone Spiccia
,
Lisandra L. Martin
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Peptides@mica: from affinity to adhesion mechanism
Investigating the adsorption of peptides on inorganic surfaces, on the molecular level, is fundamental for medicinal and analytical …
Anika Gladytz
,
Torsten John
,
Thomas Gladytz
,
Rayk Hassert
,
Mareen Pagel
,
Herre Jelger Risselada
,
Sergej Naumov
,
Annette G. Beck-Sickinger
,
Bernd Abel
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Multifunctional Coating Improves Cell Adhesion on Titanium by using Cooperatively Acting Peptides
Promotion of cell adhesion on biomaterials is crucial for the long-term success of a titanium implant. Herein a novel concept is …
Mareen Pagel
,
Rayk Hassert
,
Torsten John
,
Klaus Braun
,
Manfred Wießler
,
Bernd Abel
,
Annette G. Beck-Sickinger
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